Toxicological Trivia from February 04, 2010: The Dimethyl fumarate is one of the most powerful known skin sensitizers. May cause allergic reactions in ratios of only 1 ppm (part per million). Eczema are often difficult to treat. It is used: a) As a fungicide in shipping and storage of goods; b) In medicine, to combat skin diseases including psoriasis; c) Both previous assertions are correct.