J. C. Piola (*); D.B. Prada (*); M. Evangelista (*). Rev Med Rosario 65 (1);1999, 7-12.
(*) Servicio de Toxicología del Sanatorio de
Niños, Rosario
Medication error (ME) constituted an interesting group of accidental poisonings
that were assisted by us between 1990 and 1997. The problems and sources of ME
are multidisciplinary and multifactorial. Pharmacists, physicians, nurses,
supportive personnel (e.g., pharmacy technicians), patients and their caregivers
and others may make ME. This work presents the data of 37O patients with ME that
were assisted in Servicio de Toxicología del Sanatorio de Niños (SERTOX) between
January 1990 and December 1997. The patients age was in the range of O-2O years
in 73% of cases. 68.8% of patients under 20 years were male and 60% of over 20
years patients were female. The consultation was more frequent during Monday,
Tuesday, Friday and Sunday. The months May, June, July and September had more ME
consults; the annual ME consultation average 3.6%; 36.8% occurred between 8AM
and 14 PM; 16.3% between 14 PM and 18 PM and 34.5% between 18 PM and 24 PM.
64.5% of the ME consultation were made during the hour immediately afterwards it
happened. The types of EM considered by us were: prescribing error (7),
unauthorised drug error (122)or use of a non medicament instead of prescribed
medicament (55), not preescribed doses (142), extra doses (14), the way and/or
the celerity of administration (39), expired medicament (1). Sometimes they
could be classified on 2 or more categories because they do not exclude each
other. The 84.9% of ME were with medicaments and the 15.1 were with
non-medicaments. The more frequent ME were with the following medicameuts:
autonomic nervous systems acting Z3.3%); external use (22%); non-classified by
CIE (13.4%) and antibiotics.The more frequent non-medication ME was with
hypoclorite and others caustics (39.3%), organophosphorus anticholinesterase
insecticides and others (25%). The absorption routes were: ingestion (81.3%);
mucous (8.1%); intravenous, intramuscular and subcutaneus (6.8%); inhalation
(2.2%) and dermatological (1.6%). 61.2% were asymptomatic patients, 30.2% were
with light symptomatology. Three patients had severe symptomatology. Two
patients died. More frequent symptomatologies were neurological (36. 1%);
gastroenterological (22.2%) and others symptoms (20.8%). There are not any
data available about ME in our country. We think that collecting data is the
first step to identify the causes and prevent them. The real solutions would be
interdisciplinary. We are trying to improve our knowledge about ME in Rosario
and our region, to adapt the assistance to this reality and prevent this type of
accidents. ME should be reported to a national monitorhtg program like
Medication Errors Reporting Program of USA.